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Class Activity #3
Schizophrenia vs PTSD
I used coloc package in R to try and find a similarity or connection between schizophrenia high-risk gene loci to PTSD. I took 30 high-risk gene loci for schizophrenia and ran it through coloc.abf() and these are the plotted results.
GAMLSS
RMIT_Hw1
Random Forest in microRNA gene expression data on Infectious Mononucleosis
This study in the document had all the information on methods used to derive the NCBI gene expression data, we explore it and analyze the fold change values and get the top genes, those common to all time stamps of the mononucleosis gene expression results from Affymetrix Gene Chip Array. The micoRNA names are not recognized as genes in genecards.org and Ensembl isn't loading into my browser currently to check. The internet says they are microRNA only tried one search but they are probably the genes identified within the machine or not. Could be a separate database. MicroRNA are involved in transcription of dropping introns and forming messenger RNA from premessenger RNA and in assisting translation of the mRNA at the ribosome. They should still have genes in the DNA because they are proteins and DNA makes the proteins our bodies need and use. RandomForest predicted 100% accuracy the class in a 2 class model, but a 5 class model not at all accurate.
Tarea 2 MECU 8005
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POLS3312: Lecture 2